Nickesha C. Anderson, Ph.D Candidate
B.A. in Biology with a minor in Chemistry from Mount Holyoke College, 2011
My research project involves analysis of the molecular cues necessary for efficient generation of human embryonic stem cell (hESC) derived inhibitory interneuron progenitors in vitro. We utilize a variety of techniques like immunocytochemistry and qRT-PCR to characterize the identity of derived cells. In collaboration with the Naegele and Aaron labs, we are interested in looking at the survival, integration and differentiation potential of the neural progenitors after transplantation into the mouse hippocampus.
Christopher Chen, Ph.D Candidate
B.A. in Biology from the State University of New York at Binghamton, 2008
My work focuses on the derivation of neural progenitors of an inhibitory ventral forebrain fate from mouse embryonic stem cells. We aim to address the capacity of these cells to suppress seizures and correct cognitive dysfunction upon transplantation into our temporal lobe epileptic mouse model.
In collaboration with the Graveley lab at the University of Connecticut Health Center, transcriptome analysis using high throughput mRNA sequencing is being utilized to assess and evaluate the molecular profile of our human embryonic stem cell (hESC) derived inhibitory interneuron progenitors.
Sandy Becker, Research Technician, Emeritus
BA in History from Pomona College 1963
MALS and MA in Biology from Wesleyan
CAS in Science Journalism from Wesleyan
Studying the role of primary cilia in extraembryonic endoderm differentiation; studying the role of Wnt signaling in parietal endoderm migration.
Former Lab Members: